The Biophysical Instrumentation Facility (BIF) at MIT houses instruments that aid in the elucidation of macromolecular structures and interactions.

The BIF is located in the MIT Biology Building (68-470: https://whereis.mit.edu/) on Ames Street near Kendall Square. The BIF is used by MIT researchers in Chemistry, Biology, Biological Engineering, and Chemical Engineering and is available to all members of the MIT community and beyond.

The BIF maintains A JASCO Circular Dichroism Spectrometer, a Prometheus PANTA nanoDSF with parallel DLS, a Sartorius Octet R8 Biolayer Interferometry system, a Refeyn-Two Mass Photometer, a Malvern PEAQ-Isothermal Titration Calorimeter, a Wyatt Dynamic Light Scattering instrument, and an Agilent HPLC with SEC-MALS system.

Snap shots of the BIF INSTRUMENTS - FOR MORE INFORMATION SEE LINKS IN THE HEADER

Dr. Ky Lowenhaupt, who manages the BIF, is available to train new users and advise those considering the instruments' potential application in the facility.

ONLINE SIGN-UP FOR TRAINED MIT USERS IS ACTIVE

For all inquiries, please get in touch with Dr. Ky Lowenhaupt - bif@mit.edu

The BIF is a BL1 facility

Please do not bring hazardous or toxic chemicals into the BIF, as all of the instruments are on the open benchtops. Thank you!

Prof. Barbara Imperiali established the BIF through NIH, NSF, HHMI, and MIT funding.